Progress report 2009 : replacing, reducing and refining use of animals in research : genomics & biotechnology for health
Replacing the need for animal experiments, reducing the number of animals required and refining the procedures to improve animal welfare when the use of animals is unavoidable, also known as the 3Rs Principle, are the underlying concepts for the development of alternative testing strategies used in pharmaceutical discovery and development, and in safety assessment of chemicals. Research into alternative testing strategies is part of the EU’s Sixth and Seventh RTD Framework Programmes (FP6 and FP7: 2002-2013). The purpose of this publication is to present past and ongoing activities in this... field of FP6 and FP7 and the results generated. A particular focus of the work is on the development of in vitro methods and on methods that can be validated to meet international standards, achieve approval of regulatory authorities and be adopted by industry.